Dr Claudio Vergari
Current research interests
My main interest in research is the biomechanical characterization of soft tissue. It is a fascinating field since it couples experimental engineering and medical issues. In particular, I specialize on the development and application of novel techniques to investigate soft tissue mechanical properties. For instance, during my PhD I worked on a technique based on quantitative ultrasound to non-invasively measure the force applied to superficial tendons, as well as their elastic modulus. More recently, I worked with ultrasound elastography to non-invasively assess intervertebral disc properties.
Currently, I am applying nonlinear microscopy techniques to investigate needle injury to the intervertebral disc. I collaborate on this project with Prof C. Peter Winlove, Dr Jude Meakin and Dr Jessica Mansfield.
Positions and Employment
2015 - present Research Fellow at the University of Exeter. Needle Injury to the Annulus of the Intervertebral Disc: Mechanisms and Minimisation with Prof. C.P. Winlove. Project funded by the Henry Smith Charity.
2012 - 2015 Postdoctoral fellow at the Laboratoire de Biomécanique, Arts et Métiers Paristech, Paris, France. Personalized biomechanical modeling of scoliotic spine with Prof. W. Skalli. Project funded by the BiomecAM chair program on subject-specific musculoskeletal modelling.
2011 - 2012 Postdoctoral fellow in the Unité INRA-ENVA 957 Biomécanqiue et Pathologie Locomotrice du Cheval, Ecole Nationale Vétérinaire d'Alfort, Maisons-Alfort, France. Project on the calibration of axial speed of sound measurements in human and equine tendons.
2008 - 2011 PhD student in biomechanics and ultrasound propagation in the Unité INRA-ENVA 957 Biomécanqiue et Pathologie Locomotrice du Cheval (Prof. Nathalie Crevier-Denoix), ENVA, Maisons-Alfort, France, in collaboration with IFFSTAR/INRETS (Prof. David Mitton) and Université Pierre et Marie Curie (Dr Pascal Laugier).
2007 Product specialist in electrosurgery at LED spa, Aprilia, Italy.
2005 Internship at the Medical Engineering Service, Tor Vergata General Hospital, Rome, Italy.
Publications and patents
C.Vergari, J. Mansfield, J. R. Meakin, P. C. Winlove, In press. Lamellar and fibre bundle mechanics of the annulus fibrosus in bovine intervertebral disc. Acta Biomaterialia.
C.Vergari, I. Courtois, E. Ebermeyer, H. Bouloussa, R. Vialle, W. Skalli, In press. Experimental validation of a patient-specific model of orthotic action in adolescent idiopathic scoliosis. European Spine Journal.
C.Vergari, G. Dubois, R. Vialle, J.-L. Gennisson, M. Tanter, J. Dubousset, P. Rouch, W. Skalli, 2016. Lumbar annulus fibrosus biomechanical characterization in children by ultrasound shear wave elastography. European Radiology 26, 4:1213-1217.
G.Dubois, W. Kheireddine, C.Vergari, D. Bonneau, P. Thoreux, P. Rouch, M. Tanter, J.L. Gennisson, W. Skalli, 2015. A reliable protocol for shearwave elastography of lower limb muscles at rest and during passive stretching. Ultrasound in Medicine & Biology (41), 9:2284-2291.
C. Vergari, G. Ribes, B. Aubert, C. Adam, L. Miladi, B. Ilharreborde, K. Abelin-Genevois, P. Rouch, W. Skalli, 2015. Evaluation of a patient-specific finite element model to simulate conservative treatment in adolescent idiopathic scoliosis. Spine Deformity (3), 1:4-11.
C. Vergari, P.Rouch, G. Dubois, D. Bonneau,J. Dubousset, M. Tanter, J.L. Gennisson, W. Skalli (2014). Non-invasive biomechanical characterization of intervertebral disc by shearwave ultrasound elastography: a feasibility study. European Radiology (24), 12:3210-3216.
C. Vergari, P.Rouch, G. Dubois, D. Bonneau,J. Dubousset, M. Tanter, J.L. Gennisson, W.Skalli, 2014. Intervertebral disc characterization by shear wave elastography: an in-vitro preliminary study. Journal of Engineering in Medicine (228), 6:607-615.
B. Aubert B., C. Vergari, B. Ilharreborde, Courvoisier A., W. Skalli (In Press). 3D reconstruction of ribcage geometry from biplanar radiographs using a statistical parametric model approach. Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization.
N. Crevier-Denoix, S. Falala, L. Holden-Douilly, M. Camus, J. Martino, B. Ravary-Plumioën, C. Vergari, L. Desquilbet, J.-M. Denoix, H. Chateau, P. Pourcelot, 2013. Comparative kinematic analysis of the leading and trailing forelimbs of horses cantering on a turf and a synthetic surface. Equine Veterinary Journal (IF: 2.286) (45), S45: 54-61.
H. Chateau, M. Camus, L. Holden-Douilly, S. Falala, B. Ravary-Plumioën, C. Vergari, J. Lepley, J.M. Denoix, P. Pourcelot, N. Crevier-Denoix, 2013. Kinetics of the forelimb in horses circling on different ground surfaces at the trot. The Veterinary Journal (IF: 2.424) (198),S1:e20–e26.
N. Crevier-Denoix, B. Ravary-Plumioën, C. Vergari, M. Camus, L. Holden-Douilly, S. Falala, H. Jerbi, L. Desquilbet, H. Chateau, J.M. Denoix and P. Pourcelot, 2013. Comparison of superficial digital flexor tendon loading on asphalt and on sand in horses at the walk and trot. The Veterinary Journal (IF: 2.424) (198), S1: e130–e136.
N. Crevier-Denoix, P. Pourcelot, L. Holden-Douilly, M. Camus, S. Falala, B. Ravary-Plumioën, C. Vergari, L. Desquilbet and H. Chateau, 2013. Discrimination of two equine racing surfaces based on forelimb dynamic and hoof kinematic variables at the canter. The Veterinary Journal (IF: 2.424) (198): e124-e129.
Vergari, C., Ravary-Plumioën B., Evrard, D., Laugier, P., Mitton, D., Pourcelot P. and Crevier-Denoix, N., 2012. Axial Speed of Sound is Related to Tendon's Nonlinear Elasticity. Journal of Biomechanics (45), 2, 263-268.
Vergari, C., Pourcelot P., Ravary-Plumioën B., Dupays A.G., Denoix J.M., Mitton D., Laugier P. and Crevier-Denoix N., 2012. First Application of Axial Speed of Sound to Follow up Injured Equine Tendons. Ultrasound in Medicine & Biology (38), 1, 162-167.
Vergari, C., Pourcelot, P., Ravary-Plumioën, B., Dupays, A.G., Jacquet, S., Audigié, F., Denoix, J.M., Laugier, P., Mitton, D., and Crevier-Denoix, N., 2012. Axial speed of sound for the monitoring of injured equine tendons: a preliminary study. Journal of Biomechanics (45), 1, 53-58.
Vergari, C., Pourcelot, P., Holden, L., Ravary-Plumioën, B., Gerard, G., Laugier, P., Mitton, D., and Crevier-Denoix, N., 2011. True Stress and Poisson's Ratio of Tendons during Loading. Journal of Biomechanics, (44), 719-724.
Vergari, C., Pourcelot, P., Holden, L., Ravary-Plumioën, B.,Laugier, P., Mitton, D., and Crevier-Denoix, N., 2010. A Linear Laser Scanner to Measure Cross-Sectional Shape and Area of Biological Specimens During Mechanical Testing. Journal of Biomechanical Engineering, (132), 10, 105001-105007.
Inventor of a patented anchorage device for wheelchairs (patent number: 0001389034).