Publications
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| 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
2024
- Jackson L, Weedon MN, Green HD, Mallabar-Rimmer B, Harrison JW, Wood AR, Ruth KS, Tyrrell J, Wright CF. (2024) Response to Penetrance estimates of hereditary cancers in a population setting using UK Biobank data, BJC Reports, volume 2, no. 1, DOI:10.1038/s44276-023-00031-9.
- Loginovic P, Wang F, Li J, Ferrat L, Mirshahi UL, Rao HS, Petzold A, Tyrrell J, Green HD, Weedon MN. (2024) Applying a genetic risk score model to enhance prediction of future multiple sclerosis diagnosis at first presentation with optic neuritis, Nature Communications, volume 15, no. 1, article no. 1415, DOI:10.1038/s41467-024-44917-9. [PDF]
2023
- Mallabar-Rimmer B, Merriel SWD, Webster AP, Wood AR, Barclay M, Tyrrell J, Ruth KS, Thirlwell C, Oram R, Weedon MN. (2023) Colorectal cancer risk stratification using a polygenic risk score in symptomatic patients presenting to primary care – a UK Biobank retrospective cohort study, DOI:10.1101/2023.12.08.23299717. [PDF]
- Jackson L, Weedon MN, Green HD, Mallabar-Rimmer B, Harrison JW, Wood AR, Ruth KS, Tyrrell J, Wright CF. (2023) Influence of family history on penetrance of hereditary cancers in a population setting, eClinicalMedicine, volume 64, pages 102159-102159, article no. 102159, DOI:10.1016/j.eclinm.2023.102159. [PDF]
- Karageorgiou V, Casanova F, O'Loughlin J, Green H, McKinley TJ, Bowden J, Tyrrell J. (2023) Body mass index and inflammation in depression and treatment-resistant depression: a Mendelian randomisation study, BMC Med, volume 21, no. 1, DOI:10.1186/s12916-023-03001-7. [PDF]
- Green HD, Merriel SWD, Oram RA, Ruth KS, Tyrrell J, Jones SE, Thirlwell C, Weedon MN, Bailey SER. (2023) Response to: Genetic risk scores may compound rather than solve the issue of prostate cancer overdiagnosis (BJC-LT3342090), Br J Cancer, volume 128, no. 4, pages 487-488, DOI:10.1038/s41416-022-02081-1. [PDF]
2022
- Oram R, Loginovic P, Ferrat L, Green H, Weedon M, Tyrrell J, Petzold A, Braithwaite T. (2022) Applying a genetic risk score model to enhance prediction of future Multiple Sclerosis diagnosis at first presentation with optic neuritis: a cohort study in the UK Biobank, DOI:10.21203/rs.3.rs-2383733/v1.
- Tyrrell J, Gillett A, Casanova F, Young K, Green H, Lewis C, Hagenaars S. (2022) The impact of depression diagnosis on diabetes and lifetime hyperglycaemia, World Congress of Psychiatric Genetic (WCPG), Florence, Italy, 13th - 17th Sep 2022, DOI:10.1016/j.euroneuro.2022.07.042.
- Karageorgiou V, Casanova F, O'Loughlin J, Green H, McKinley TJ, Bowden J, Tyrrell J. (2022) Body Mass Index And Inflammation In Depression And Treatment-Resistant Depression: A Mendelian Randomization Study, DOI:10.21203/rs.3.rs-1985746/v1. [PDF]
- Green H, Merriel SWD, Oram R, Ruth K, Tyrrell J, Jones S, Thirlwell C, Gillings M, Weedon M, Bailey SER. (2022) Applying a genetic risk score for prostate cancer to men with lower urinary tract symptoms in primary care to predict prostate cancer diagnosis: a cohort study in the UK Biobank, DOI:10.1101/2022.01.21.22269629.
- Gillett AC, Hagenaars SP, Handley D, Casanova F, Young KG, Green H, Lewis CM, Tyrrell J. (2022) The impact of major depressive disorder on glycaemic control in type 2 diabetes: a longitudinal cohort study using UK Biobank primary care records, DOI:10.1101/2022.01.13.22269229. [PDF]
2021
- Hagenaars S, Casanova F, Gillett A, Green H, Lewis C, Tyrrell J. (2021) ASSESSING THE IMPACT OF DEPRESSION DIAGNOSIS ON DIABETES AND LIFETIME HYPERGLYCAEMIA, EUROPEAN NEUROPSYCHOPHARMACOLOGY, volume 51, pages E90-E90, DOI:10.1016/j.euroneuro.2021.07.178. [PDF]
- Nice R, Chanchlani N, Kennedy NA, Green HD, Lin S, Gordon C, Chee D, Hamilton B, Bewshea C, Goodhand J. (2021) POSITIVITY THRESHOLDS OF TOTAL INFLIXIMAB AND ADALIMUMAB ANTI-DRUG ANTIBODY ASSAYS AND IMPACT IN CLINICAL PRACTICE, GUT, volume 70, pages A103-A103, DOI:10.1136/gutjnl-2020-bsgcampus.193. [PDF]
- Green HD, Young KG, Jones AG, Weedon MN, Dennis JM. (2021) Using joint models to adjust for informative drop-out when modelling a longitudinal biomarker: an application to type 2 diabetes disease progression, DOI:10.1101/2021.06.17.448796. [PDF]
- Heald AH, Martin S, Fachim H, Green HD, Young KG, Malipatil N, Siddals K, Cortes G, Tyrrell J, Wood AR. (2021) Genetically defined favourable adiposity is not associated with a clinically meaningful difference in clinical course in people with type 2 diabetes but does associate with a favourable metabolic profile, Diabetic Medicine, volume 38, no. 9, DOI:10.1111/dme.14531. [PDF]
- Nice R, Chanchlani N, Green H, Bewshea C, Ahmad T, Goodhand JR, McDonald TJ, Perry MH, Kennedy NA. (2021) Validating the positivity thresholds of drug-tolerant anti-infliximab and anti-adalimumab antibody assays, Aliment Pharmacol Ther, volume 53, no. 1, pages 128-137, DOI:10.1111/apt.16135. [PDF]
2020
- Nice R, Chanchlani N, Green H, Bewshea C, Kennedy N, Ahmad T, Goodhand J, McDonald T, Perry M. (2020) OP21 Positivity thresholds of total infliximab and adalimumab anti-drug antibody assay: The prevalence of clearing and transient anti-drug antibodies in a national therapeutic drug monitoring service, Journal of Crohn's and Colitis, volume 14, no. Supplement_1, pages s018-s019, DOI:10.1093/ecco-jcc/jjz203.020.
- Green HD, Jones A, Evans JP, Wood AR, Beaumont RN, Tyrrell J, Frayling TM, Smith C, Weedon MN. (2020) A genome wide association study of frozen shoulder identifies a common variant of WNT7B and diabetes as causal risk factors, DOI:10.1101/2020.11.13.20224360. [PDF]
- Green HD, Beaumont RN, Wood AR, Hamilton B, Jones SE, Goodhand JR, Kennedy NA, Ahmad T, Yaghootkar H, Weedon MN. (2020) Genetic evidence that higher central adiposity causes gastro-oesophageal reflux disease: a Mendelian randomization study, International Journal of Epidemiology, volume 49, no. 4, pages 1270-1281, DOI:10.1093/ije/dyaa082. [PDF]
- Hamilton B, Green H, Heerasing N, Hendy P, Moore L, Chanchlani N, Walker G, Bewshea C, Kennedy NA, Ahmad T. (2020) Incidence and prevalence of inflammatory bowel disease in Devon, UK, Frontline Gastroenterology, volume 12, no. 6, pages 461-470, DOI:10.1136/flgastro-2019-101369. [PDF]
- Walker GJ, Lin S, Chanchlani N, Thomas A, Hendy P, Heerasing N, Moore L, Green HD, Chee D, Bewshea C. (2020) Quality improvement project identifies factors associated with delay in IBD diagnosis, Alimentary Pharmacology & Therapeutics, volume 52, no. 3, pages 471-480, DOI:10.1111/apt.15885. [PDF]
- Lin S, Green HD, Hendy P, Heerasing NM, Chanchlani N, Hamilton B, Walker GJ, Heap GA, Hobart J, Martin RJ. (2020) Clinical Features and Genetic Risk of Demyelination Following Anti-TNF Treatment, J Crohns Colitis, volume 14, no. 12, pages 1653-1661, DOI:10.1093/ecco-jcc/jjaa104. [PDF]
2019
- Green H, Beaumont R, Jones S, Yaghootkar H, Wood A, Goodhand J, Kennedy N, Ahmad T, Frayling T, Weedon M. (2019) MODIFIABLE RISK FACTORS FOR GASTRO-OESOPHAGAL REFLUX DISEASE: A MENDELIAN RANDOMISATION STUDY, GUT, volume 68, pages A139-A139, DOI:10.1136/gutjnl-2019-BSGAbstracts.263. [PDF]
- Walker G, Lin S, Thomas A, Chanchlani N, Moore L, Hendy P, Heerasing N, Green H, Mole S, Bewshea C. (2019) PROSPECTIVE COHORT TO IDENTIFY FACTORS ASSOCIATED WITH DIAGNOSTIC DELAY IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE, GUT, volume 68, pages A244-A245, DOI:10.1136/gutjnl-2019-BSGAbstracts.467. [PDF]
- Green HD, Beaumont RN, Thomas A, Hamilton B, Wood AR, Sharp S, Jones SE, Tyrrell J, Walker G, Goodhand J. (2019) Genome-Wide Association Study of Microscopic Colitis in the UK Biobank Confirms Immune-Related Pathogenesis, J Crohns Colitis, volume 13, no. 12, pages 1578-1582, DOI:10.1093/ecco-jcc/jjz104. [PDF]
- Walker G, Lin S, Chanchlani N, Thomas A, Moore L, Hendy P, Heerasing N, Green H, Bewshea C, Goodhand J. (2019) Prospective cohort to identify factors associated with a delay in diagnosis in patients with inflammatory bowel disease, JOURNAL OF CROHNS & COLITIS, volume 13, pages S181-S181, DOI:10.1093/ecco-jcc/jjy222.306. [PDF]
- Bewshea CM, Ahmad T, Kennedy N, Goodhand J, McDonald T, Green H. (2019) Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study, Lancet Gastroenterology and Hepatology, DOI:10.1016/S2468-1253(19)30012-3.
2018
- Green H, Hamilton B, Walker G, Goodhand J, Kennedy N, Ahmad T, Weedon M. (2018) GWAS OF MICROSCOPIC COLITIS IN THE UK BIOBANK CONFIRMS ASSOCIATION WITHIN THE HLA REGION, GUT, volume 67, pages A182-A183, DOI:10.1136/gutjnl-2018-BSGAbstracts.362. [PDF]
2017
- Green HD, Thomas G, Terry JR. (2017) Signal reconstruction of pulmonary vein recordings using a phenomenological mathematical model: Application to pulmonary vein isolation therapy, Frontiers in Physiology, volume 8, no. JUL, DOI:10.3389/fphys.2017.00496.