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Dr Ryan Stuart Edginton

Research Assistant (Biomedical Physics)

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Ryan completed his MPhys undergraduate masters degree at the University of Exeter in 2013, following a two-year research project investigating the impact of apoptosis on the electric dipole potential of the red blood cell membrane.

He recently obtained his PhD under the supervision of Prof. Francesca Palombo, Prof. Nick Stone and Prof. C. Peter Winlove at Exeter; studying the hierarchical structure and mechanics of collagen and elastin under different conditions of hydration. Subsequently as a research assistant, he has supported spectral investigations of the neurodegenerative disease, Tauopathy, and of mucins as a diagnostic marker of gastro-intestinal cancers. He has experience of tissue cryosectioning, and is practised in the application of polarised micro-Raman and Brillouin light scattering spectroscopies, together with ATR-FTIR, polarisation resolved micro-FTIR imaging, and quasi-static mechanical testing.

During his doctoral studies, Ryan performed the role of Outreach Officer for the Biomedical Physics Group, and was an academic Instructor to the Gold medal winning University of Exeter International Genetically Engineered Machines (iGEM) teams. He is passionate about promoting interdisciplinary collaboration as the future of scientific research, and inspiring curiosity in young people. . . and in those whose cells aren't dividing as efficiently as they maybe used to!

 

Find Me On:

LinkedIn  |   Twitter @EdgintonRS   |  ResearchGate

 

 

Education & Employment

  • 2016 - 2018     Research Assistant (Exeter) - Wellcome Trust ISSF Seed-Corn Fund Rounds 3 & 5
  • 2014 - 2018     Doctor of Philosophy in Physics (PhD) - University of Exeter
  • 2009 - 2013     Master of Physics (MPhys Hons.) - University of Exeter

 

Publications

  • Stantchev, R.I., Edginton, R.S. et al, "Subwavelength hyperspectral THz studies of articular cartilage", Scientific Reports, 8: 6924 (2018)
  • Edginton, R.S. et al, "Dual scale biomechanics of extracellular matrix proteins probed by Brillouin scattering and quasistatic tensile testing", Proc. SPIE 10504, Biophysics, Biology and Biophotonics III: The Crossroads, 105040J (2018)
  • Edginton, R.S. et al, "Preparation of Extracellular Matrix Protein Fibres for Brillouin Spectroscopy", J. Vis. Exp. 115: e54648 (2016)
  • Palombo, F., Edginton, R.S. et al, "Biomechanics of fibrous proteins of the extracellular matrix studied by Brillouin scattering", J. R. Soc. Interface 11: 20140739 (2014)

 

Conferences & Invited Talks

  • "Festive Frequency Shifts: Spectroscopy and the Molecular Markers of Disease" - (Invited Talk) CEMPS Christmas Lectures 2018 (Exeter - 19/12/2018)
  • "The Hierarchical Water-Mediated Mechanics of the Extracellular Matrix: A Multimodal Approach" - (Poster Presentation) 1st BioBrillouin Meeting (Vienna - 15/09/2017)
  • “A multiscale analysis of the mechanical properties of the fibrous proteins of the extracellular matrix using Brillouin light scattering spectroscopy“ - (Oral Presentation & Poster) SciX2016 (Minneapolis - 21/09/2016)
  • "More than just a laser pointer: Light Scattering and the Physics of Biology" - (Invited Talk) Pint of Science 2016 (Exeter - 25/05/2016)
  • "Brillouin Light Scattering Spectroscopy and Elasticity in Hydrated Connective Tissue" - (Oral Presentation) 13th Martin & Willis Student Meeting - Infrared & Raman Discussion Group (Exeter - 26/08/2015)
  • "The Effect of Hydration on the Macroscopic Elastic Modulus of Type I Collagen and Elastin Fibres" - (Oral Presentation) 21st Congress of the European Society of Biomechanics (Prague - 06/07/2015)
  • "The Biophysics of the Extracellular Matrix" - (Invited Talk) University of Perugia Department of Physics (Perugia - 12/03/2015) 

 

Awards & Competitions

  • Winner: Best Final Year Poster - "Brillouin Light Scattering Spectroscopy: Sensing the Elasticity of Connective Tissue"  (Exe-BioCon 2016, Exeter - 14/06/2016)
  • SET for Britain 2016 Finalist - "Brillouin Light Scattering Spectroscopy: Sensing the Elasticity of Connective Tissue" (Houses of Parliament, Westminster - 07/03/2016)

 

Funding

  • £300 - "IPEM Student and Trainee Travel Grant" - to support attendance to SciX2016, Minneapolis, USA (AUG 2016)
  • £175 - "C R Barber Trust Fund" - for accommodation at SciX2016, Minneapolis, USA (JULY 2016)
  • £300 - "IOP Student Conference Fund" - for accommodation at SciX2016, Minneapolis, USA (JULY 2016)
  • £1000 - "Santander Postgraduate Research Award" - for one month residential and facilities usage at the Department of Physics, University of Perugia, Italy (JAN 2015)

 

Contributions to the Community

  • Exeter iGEM Academic Instructor (2014 - 2017) 
  • iGEM 2016 Giant Jamboree Judge - Hynes Convention Centre, Boston (27/10/2016 - 31/10/2016)
  • iGEM 2015 Giant Jamboree Judge - Hynes Convention Centre, Boston (25/09/2015 - 28/09/2015)

 

Outreach & Engagement

  • Institute of Physics Festival of Physics: "New Approach for Cancer Screening and Diagnosis" - Exeter (Demonstrator - 08/12/2018)
  • Exeter Progression in Physics: Biomedical Physics - Exeter (Demonstrator - 12/04/2017)
  • Exeter Progression in Physics: Biomedical Physics - Exeter (Organiser - 06/04/2016)
  • University of Exeter Community Day - Exeter (20/03/2016)
  • Britain Needs Scientists: Speed Dating - Exeter (16/03/2016)
  • Royal Society of Chemistry ChemNet: "Meet the BioSpec Team @ Exeter" - Exeter (14/12/2015)

 

Memberships

  • Associate Member of the Institute of Physics (IOP)
  • Student Member of the European Society of Biomechanics
  • Associate Member of the Institute of Physics and Engineering in Medicine (IPEM)
  • Student Member of the Society of Applied Spectroscopy
  • Student Member of the International Society for Clinical Spectroscopy (CLIRSPEC)