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Dr Martha Vardaki

Deep Raman Scientist

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Martha Vardaki obtained her BSc degree in Pharmacy from the University of Patras, Greece, in 2009, completing the final of the 5-year curriculum studying the main ingredients of Crocus endemic species using High-performance liquid chromatography (HPLC). Carrying on the field of analytical techniques, she obtained a MSc in Industrial Pharmacy & Pharmaceutical Analysis, studying osteoarthritis on human femoral heads by the means of Raman microscopy.

She obtained her PhD in ‘BioSpec’ research group at the University of Exeter. Under the supervision of  Prof. Nick Stone  in Exeter and  Prof. Pavel Matousek  in STFC, while developing real-time Raman techniques for cancer diagnosis.

Martha is currently working as a Raman scientist in 'BioSpec' group with research focusing on ovarian cancer blood samples and spine sections study by means of Raman spectroscopy.

Strongly motivated by her pharmacy background, Martha is keen on the diverse ways that the interaction of light and matter can assist disease diagnosis. Her current research focuses on the application of deep Raman techniques to prostate cancer diagnosis. She studies the spectroscopic behaviour and Raman signal distribution, both in tissue phantoms and prostate human tissue, in collaboration with clinical partners in the Royal Devon & Exeter NHS Foundation Trust. In parallel, she explores the detection of potential bladder cancer biomarkers in urine samples. So far, Martha has presented a number of lectures/posters in various national and international conferences, and co-authored peer-reviewed papers outlining the very important role of Raman spectroscopy in current diagnostics.

 

Education

  • 2004-2009: BSc in Pharmacy (5-year curriculum), Department of Pharmacy, University of Patras, Greece Diploma work title: ‘’Development of analytical methodology using HPLC for the isolation of the main ingredients of Crocus endemic species.’’
  • 2010: Pharmacist license
  • 2011-2013: MSc in Industrial Pharmacy and Drug Analysis Instrumental Pharmaceutical Analysis lab, Department of pharmacy, University of Patras, Greece Thesis title: ‘’Development of a Novel Diagnostic Method for Bone and Cartilage Diseases’’
  • 2013-present: PhD Candidate, Department of Physics, University of Exeter Project title: ‘’Development of deep Raman techniques as a novel prospect for prostate cancer detection’’ -Collaboration with STFC-RAL and Royal Devon & Exeter NHS Foundation Trust

Grants/ Awards

    • In July 2014, she was awarded with an ABS (Association of British Spectroscopists) Trust Bursary to attend the international spectroscopy conference  SPEC  in Poland
    • In April 2015, her work won the title of the ‘’Most Innovative Poster’’ in Exeter University’s Postgraduate Research Showcase.
    • In August 2015, she was awarded with a RSC travel grant for attending and presenting her work in the international conference SciX in Providence, RI, USA

Publications

  • Martha Z. Vardaki, Hannah Sheridan, Nicholas Stone, Pavel Matousek, ‘'Determination of Depth in Transmission Raman Spectroscopy in Turbid Media Using a Beam Enhancing Element’’, Applied Spectroscopy, 2017, DOI: 10.1177/0003702817691540
  • Samuel Hornett, Rayko Stantchev, Martha Z. Vardaki, Chris Beckerleg, Euan Hendry, ‘'Subwavelength THz imaging of graphene photoconductivity;’, Nanoletters, 2016, 16(11), 7019-7024
  • Martha Z. Vardaki, Nicholas Stone, Pavel Matousek,‘'Characterisation of signal enhancements achieved when utilizing a photon diode in deep Raman spectroscopy of tissue’’, Biomedical Optics Express, 2016, 7, 2130-2141
  • Martha Z. Vardaki, Ben Gardner, Nicholas Stone, Pavel Matousek, ‘'Studying the distribution of deep Raman spectroscopy signals using liquid tissue phantoms with varying optical properties’’, Analyst, 2015, 140, 5112
  • Malvina G. Orkoula, Martha Z. Vardaki and Christos G. Kontoyannis, ‘’Study of Bone Matrix Changes Induced by Osteoporosis in Rat Tibia Using Raman Spectroscopy’’, Vibrational Spectroscopy, 63 (2012) 404-408. 

Selected presentations in Conferences

  • Martha Z. Vardaki, Pavel Matousek, Nicholas Stone,Studying the distribution of deep Raman spectroscopy signals using liquid tissue phantoms with varying optical properties, Providence, RI, USA, SciX, 27 September- 2 October 2015. Oral Presentation.
  • Martha Z. Vardaki, Ben Gardner, Pavel Matousek, Nicholas Stone, Studying the distribution of deep Raman spectroscopy signals in prostate liquid tissue phantoms, Exeter, IRDG, 26-27 August 2015. Oral Presentation.
  • Martha Z. Vardaki, Ben Gardner, Pavel Matousek, Nicholas Stone, Studying the distribution of deep Raman spectroscopy signals in prostate liquid tissue phantoms, Exeter, Clirspec Network Conference, 20-22 April 2015. Oral Presentation.
  • Martha Z. Vardaki, P.Matousek, J. McGrath, N. Stone. Can light help us diagnose prostate cancer? SET for Britain, House of Commons, London, 9 March 2015. (Poster Presentation)
  • Martha Z. Vardaki, P. Matousek, N. Stone, Development of deep Raman spectroscopy for prostate cancer diagnosis, Krakow, 17-22 August 2014. Oral Presentation.
  • Martha Z. Vardaki, Dionysios J. Papachristou, Panagiotis Megas, Sofia Panteliu, Christos G. Kontoyannis and Malvina G. Orkoula. Raman spectroscopy of articular cartilage and subchondral bone on osteoarthritic human femoral heads. 21st Panhellenic Congress of Chemistry, Thessaloniki, December 2011. (Oral Presentation)

Public Talks

 

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