Tuesday 24 Sep 2013Spatiotemporal organization of brain activity at rest

Viktor Jirsa - AIX-Marseille

HAR170 11:00-12:00

Resting-state networks (RSNs), which have become a main focus in neuroimaging research, can be best simulated by large-scale cortical models in which networks teeter on the edge of instability. In this state, the functional networks are in a low firing stable state while they are continuously pulled towards multiple other configurations. Small extrinsic perturbations can shape taskrelated network dynamics, whereas perturbations from intrinsic noise generate excursions reflecting the range of available functional networks. This is particularly advantageous for the efficiency and speed of network mobilization. Thus, the resting state reflects the dynamical capabilities of the brain, which emphasizes the vital interplay of time and space. In this article, we propose a new theoretical framework for RSNs that can serve as a fertile ground for empirical testing

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