Photo of Mr Thomas Holding

Mr Thomas Holding



Telephone: 01326 259285

I am a PhD student looking at the evolution of malarial virulence. P. falciparum is a single celled parasite responsible the most malarial deaths in humans. In order to increase transmission between hosts, the parasite has evolved sophisticated strategies to evade the immune system. In turn, this can affect the severity of an infection. I am interested in using computational and mathematical models to better understand these interactions.

Before joining the Centre for Mathematics and the Environment, I studied for my undergraduate in Computer Science at the University of East Anglia, and completed an MSc in Natural Computation at the University of York.

Research interests

  • Co-evolutionary dynamics, particularly between pathogens and their hosts.
  • Feedback between the physical environment and biosphere.
  • Machine learning to model or predict biological systems.