About us

Based in the brand-new, world-class £52.5 million Living Systems Institute on the University of Exeter's Streatham Campus, the Centre for Predictive Modelling in Healthcare at the University of Exeter was established in January 2016 through a £2 million award from the EPSRC.

Led by Professor John Terry, the Centre brings together a world-leading team of mathematicians, statisticians and clinicians with a range of industrial partners, people with lived experience of chronic health conditions and other stakeholders to focus on the development of new methods for managing and treating noncommunciable disorders using predictive mathematical and statistical models. In addition to EPSRC support, researchers within the Centre are supported by the MRC, the Wellcome Trust and Epilepsy Research UK.

Our focus is on 'dynamic' health conditions such as autoimmune disease, cardiac arrhythmias, diabetes and epilepsy. Here we aim to revolutionise the clinical management of these disorders through better understanding the fundamental mechanisms of these disorders, as well as the development of mathematically-underpinned decision support systems. In the longer term these will enable doctors and clinicians to make enhanced diagnosis and prognosis through enhanced interrogation of routinely acquired patient data.

The Centre has 6 strategic objectives:

  1. To deliver excellence in mathematical and computational research;
  2. To drive clinical translation of fundamental research;
  3. To establish significant industry engagement enabling exploitation of IP;
  4. To engage and involve the public and people with lived experience in co-creating research;
  5. To build long-term international partnerships;
  6. To develop cross-College educational opportunities at all levels.

To measure success against these objectives the Centre’s Steering Group has agreed a set of Key Performance Indicators.

The research undertaken by the Centre can be divided into three overlapping themes:

  • Theme 1 is developing the mathematical and statistical underpinning methods for dealing with transient nonlinear systems that will be used in the other themes. It is examining both continuum and network models and uncertainty quantification for linking them to data.
  • Theme 2 is constructing clinically relevant mathematical and computational models of electrophysiological and neuroendocrine processes.
  • Theme 3 is prototyping and exploring preclinical discovery in terms of developing new data-driven diagnostic and treatment options.

Steering Group

Our Steering Group is focussed on the Centre’s strategic aims and the interface between fundamental research and technology transfer into the clinical domain, user engagement and networking activities. It includes:

  • John Terry – Professor of Biomedical Modelling, Centre Director
  • Sarah Warren – Centre Manager
  • Peter Waggett – Director of Emerging Technology, IBM UK
  • Stafford Lighman – Professor of Medicine, University of Bristol
  • Mark Richardson –  Professor of Neurology, King's College London
  • Philip Evans – GP, Associate Professor of General Practice and Primary Care and NIHR CRN Primary Care National Speciality Lead
  • Jean McEwan – Clinical cardiologist and Vice Dean Education for the Medical School, University of Exeter
  • Elaine Eggington – Principal Consultant and Director, IP Pragmatics
  • Martin Brown - Software Entrepreneur
  • Jo Welsman – Engaged Research Fellow, University of Exeter
  • Lorna Haynes – Lay representative from the Public Advisory Group
  • Stephanie Newland – EPSRC Portfolio Manager

International Advisory Board

Our International Advisory Board is made up of internationally leading academics, clinicians and healthcare representatives. The Board ensures that research activities and directions are critically evaluated against international benchmarks. It includes:

  • John Terry – Professor of Biomedical Modelling, Centre Director
  • Sarah Warren – Centre Manager
  • Paul Tiffin – Clinical Senior Lecturer in the Psychiatry of Adolescence, Durham University
  • Ya’ara Goldschmidt – Manager, Machine Learning for Healthcare and Life Sciences, IBM Research - Haifa, Israel
  • Mark Cook – Chair of Medicine and Professor and Director of Neurology, St. Vincent’s Hospital, Melbourne
  • Michael Goldstein – Professor of Statistics, Durham University
  • Carson Chow – Senior Investigator, Laboratory of Biological Modelling, National Institutes of Health (NIH)
  • Viktor Jirsa – Director of the Institute de Neurosciences des Systèmes, Marseille
  • Julian Gunn – Professor of Interventional Cardiology, University of Sheffield
  • Simon Lovestone – Professor of Translational Neuroscience, University of Oxford
  • Stephanie Newland – EPSRC Portfolio Manager

EPSRC Centres for Mathematical Sciences in Healthcare

Our Centre is one of 5 funded by the EPSRC. The others are:

If you would like to get in touch with the Centre for Predictive Modelling in Healthcare please contact the Centre Manager, Sarah Warren

 

 

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